Article
ER stress protects from retinal degeneration.
The EMBO journal - 6 May 2009
Mendes César S, Levet Clémence, Chatelain Gilles, Dourlen Pierre, Fouillet Antoine, Dichtel-Danjoy Marie-Laure, Gambis Alexis, Ryoo Hyung Don, Steller Hermann, Mollereau Bertrand
Abstract excerpt
The unfolded protein response (UPR) is a specific cellular process that allows the cell to cope with the overload of unfolded/misfolded proteins in the endoplasmic reticulum (ER). ER stress is commonly associated with degenerative pathologies, but its role in disease progression is still a matter...
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