Article
Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition.
The Journal of nutrition - 1 Jun 2009
Burdge Graham C, Lillycrop Karen A, Phillips Emma S, Slater-Jefferies Joanne L, Jackson Alan A, Hanson Mark A
Abstract excerpt
Prenatal nutritional constraint is associated with increased risk of metabolic dysregulation in adulthood contingent on adult diet. In rats, folic acid supplementation of a protein-restricted (PR) diet during pregnancy prevents altered phenotype and epigenotype in the offspring induced by the PR...
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