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Article

Activity of Temocillin against KPC-Producing <i>Klebsiella pneumoniae</i> and <i>Escherichia coli</i>

31 Mar 2009

Abstract excerpt

Temocillin, a 6-α-methoxy derivative of ticarcillin, is currently approved for treatment of infections due to members of the Enterobacteriaceae in Belgium and the United Kingdom. It is stable against hydrolysis by most β-lactamases, including extended-spectrum β-lactamases (ESBLs) and AmpC-type β-lactamases, with studies reporting MICs at which 90% of bacteria are inhibited (MIC90s) between 16 and 32 μg/ml (3, 4,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19332667
DOI: 10.1128/aac.00290-09

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