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Article

Activity of temocillin against prevalent ESBL- and AmpC-producing Enterobacteriaceae from south-east England

10 Mar 2006

Abstract excerpt

Sir, Temocillin is the 6-α-methoxy derivative of ticarcillin. This modification increases stability to β-lactamases, including AmpC and extended-spectrum types, but reduces activity against Pseudomonas aeruginosa and removes affinity for the essential penicillin-binding proteins of Gram-positive bacteria and Bacteroides spp., giving a narrow-spectrum agent with very consistent activity against...

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PMID: 16531428
DOI: 10.1093/jac/dkl043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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