Article
Quantitative in situ detection of phosphoproteins in fixed tissues using quantum dot technology.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Jul 2009
Bodo Juraj, Durkin Lisa, Hsi Eric D
Abstract excerpt
Detection and quantitation of phosphoproteins (PPs) in fixed tissues will become increasingly important as additional inhibitors of protein kinases enter clinical use and new disease entities are defined by molecular changes affecting PP levels. We characterize fixation conditions suitable for accurate PP quantitation that are achievable in a clinical laboratory and illustrate the utility of in situ quantitation...
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