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Article

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice.

Nature neuroscience - 1 May 2009

Saxena Smita, Cabuy Erik, Caroni Pico

Abstract excerpt

The mechanisms underlying disease manifestations in neurodegeneration remain unclear, but their understanding is critical to devising effective therapies. We carry out a longitudinal analysis in vivo of identified motoneurons selectively vulnerable (VUL) or resistant (RES) to motoneuron disease (amyotrophic lateral sclerosis, ALS) and show that subtype-selective endoplasmic reticulum (ER) stress responses...

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PMID: 19330001
DOI: 10.1038/nn.2297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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