Article
[Embryonal effects of t-haplotypes in mice].
Ontogenez - 1 Jan 2000
Safronova L D
Abstract excerpt
The effects of t-haplotypes on embryonic morphology in house mouse Mus musculus were described. Lethal mutations, t-haplotypes, in homozygotes induce abnormal embryogenesis and zygotic death at different developmental stages, which depends on the time of their action in ontogeny. Death commonly occurs in the first semester of pregnancy from the morula to the mature embryo stage (day 9-10), and the embryogenetic...
Topics
- Animals
- Chromosomes, Mammalian
- Embryo, Mammalian
- Female
- Gene Expression Regulation, Developmental
- Haplotypes
- Homozygote
- Mice
- Mutation
- Pregnancy