Article
Differential gene expression in the pig limbal side population: implications for stem cell cycling, replication, and survival.
Investigative ophthalmology & visual science - 1 Dec 2009
Akinci M A Murat, Turner Helen, Taveras Maria, Wolosin J Mario
Abstract excerpt
PURPOSE: To define the molecular signature of limbal SP cells and identify signaling pathways associated with the phenotype of these putative stem cells. METHODS: Primary cultures of pig limbal epithelial cells stained with Hoechst 33342 were sorted by flow cytometry into SP and non-SP cells, and purified RNA was processed for microarray analysis with an oligonucleotide spotted array. Expressed transcripts for...
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