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Article

Efficient reverse genetics generation of infectious junin viruses differing in glycoprotein processing.

Journal of virology - 1 Jun 2009

Albariño César G, Bergeron Eric, Erickson Bobbie Rae, Khristova Marina L, Rollin Pierre E, Nichol Stuart T

Abstract excerpt

The New World arenaviruses, Junin, Machupo, Guanarito, Sabia, and Chapare, are associated with rapidly progressing severe hemorrhagic fever with a high rate of case fatality in various regions of South America. The threat of natural or deliberate outbreaks associated with these viruses makes the development of preventive or therapeutic measures important. Here we describe a Junin virus functional minigenome...

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PMID: 19321606
DOI: 10.1128/JVI.00276-09
PMCID: PMC2681955

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Efficient reverse genetics generation of infectious junin viruses differing in glycoprotein processing.PMID 19321606Read ↗

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