Article
Angiotensin-converting enzyme gene insertion/deletion polymorphism in patients with chronic pancreatitis and pancreatic cancer.
Digestive surgery - 1 Jan 2011
Lukic Snezana, Nikolic Aleksandra, Alempijevic Tamara, Popovic Dragan, Sokic Milutinovic Aleksandra, Ugljesic Milenko, Knezevic Srbislav, Milicic Biljana, Dinic Dragica, Radojkovic Dragica
Abstract excerpt
The purpose of this study was to determine the frequency of angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and to investigate its role as a potential risk factor in patients with chronic pancreatitis and pancreatic cancer. Deletion polymorphism of the 287-bp fragment of intron 16 of the ACE gene results in higher levels of circulating enzyme and therefore may represent a risk...
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