Intensity of opiate withdrawal in relation to the 825C>T polymorphism of the G-protein beta 3 subunit gene.

doi:10.1016/j.pnpbp.2009.03.008

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Article

Intensity of opiate withdrawal in relation to the 825C>T polymorphism of the G-protein beta 3 subunit gene.

Progress in neuro-psychopharmacology & biological psychiatry - 15 Jun 2009

Lieb B, Bonnet U, Specka M, Augener S, Bachmann H S, Siffert W, Scherbaum N

Abstract excerpt

OBJECTIVES: The intensity of withdrawal in opiate dependence shows a high inter-individual variability. The 825C>T polymorphism (rs5443) of the G-protein beta 3 (GNB3) subunit gene has a strong influence on clinical signs of sympathetic activity in cardiac research. This study was carried out in order to test the hypothesis that carriers of the T allele have an increased sympathetic activity in opiate withdrawal....

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Identifiers

PMID: 19303909
DOI: 10.1016/j.pnpbp.2009.03.008

Genes

GNB3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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