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Article

Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis.

PLoS genetics - 1 Mar 2009

McKinney Brett A, Crowe James E, Guo Jingyu, Tian Dehua

Abstract excerpt

Evidence from human genetic studies of several disorders suggests that interactions between alleles at multiple genes play an important role in influencing phenotypic expression. Analytical methods for identifying Mendelian disease genes are not appropriate when applied to common multigenic disea...

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PMID: 19300503
DOI: 10.1371/journal.pgen.1000432
PMCID: PMC2653647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19300503-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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