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Article

Cytochrome C mutants for superoxide biosensors.

Analytical chemistry - 15 Apr 2009

Wegerich Franziska, Turano Paola, Allegrozzi Marco, Möhwald Helmuth, Lisdat Fred

Abstract excerpt

The effect of introducing positive charges (lysines) in human cytochrome c (cyt c) on the redox properties and reaction rates of cyt c with superoxide radicals was studied. The mutated forms of this electron-transfer protein are used as sensorial recognition elements for the amperometric detection of the reactive oxygen radical. The proteins were prepared by site-directed mutagenesis focusing on amino acids near...

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Identifiers

PMID: 19296689
DOI: 10.1021/ac802571h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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