O-acetylated sialic acids: multifaceted role in childhood acute lymphoblastic leukaemia.

doi:10.1002/biot.200800253

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Article

O-acetylated sialic acids: multifaceted role in childhood acute lymphoblastic leukaemia.

Biotechnology journal - 1 Mar 2009

Chowdhury Suchandra, Mandal Chitra

Abstract excerpt

Childhood acute lymphoblastic leukaemia (ALL), a malignant transformation of the lymphoblasts, is highly responsive to chemotherapy. However, due to certain inadequacy in detection of minimal residual disease (MRD), relapse is a common phenomenon. To address this question, the present review deals with the induction of an unique O-acetyl derivative of sialic acid on a few disease-associated glycoproteins and...

Topics

Acetylation
Biomarkers, Tumor
Child
Epitopes
Flow Cytometry
Genotype
Glycolipids
Glycoproteins
Humans
Immunophenotyping
Neoplasm, Residual
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Prognosis
Sialic Acids

Source

Open in PubMed

Identifiers

PMID: 19296441
DOI: 10.1002/biot.200800253

Provenance

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