Article
O-acetylated sialic acids: multifaceted role in childhood acute lymphoblastic leukaemia.
Biotechnology journal - 1 Mar 2009
Chowdhury Suchandra, Mandal Chitra
Abstract excerpt
Childhood acute lymphoblastic leukaemia (ALL), a malignant transformation of the lymphoblasts, is highly responsive to chemotherapy. However, due to certain inadequacy in detection of minimal residual disease (MRD), relapse is a common phenomenon. To address this question, the present review deals with the induction of an unique O-acetyl derivative of sialic acid on a few disease-associated glycoproteins and...
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