Article
[Perspectives of inhibition of multidrug resistance during cancer chemotherapy, in vitro and in vivo experiments].
Orvosi hetilap - 29 Mar 2009
Engi Helga
Abstract excerpt
The development of pharmacological agents able to counteract the mechanisms of multidrug resistance in oncology has remained a major goal for the past ten years. Our purpose was to find multidrug resistance reversal agents less toxic than verapamil among various synthetic compounds: cinnamylidene ketones; 1,4-dihydropyridines; phenothiazines; heat shock 90 inhibitor peptides; betti base derivative of tylosin and...
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