Article
[Interleukin-6-597G/A and -572C/G polymorphisms and risk of coronary heart disease].
Zhonghua xin xue guan bing za zhi - 1 Jun 2006
Fu Hai-xia, Li Geng-shan, Li Yan, Xu Jia-li, Zhang Jia-ying
Abstract excerpt
OBJECTIVE: To explore the relationship between interleukin-6 (IL-6) gene polymorphisms and the risk of coronary heart disease (CHD). METHODS: IL-6/-597G/A and -572C/G polymorphisms were genotyped in 245 CHD patients and 260 healthy adults by PCR-RFLP. Serum IL-6 level was examined by ELISA. Logistic regression was performed to observe the relationship between IL-6/-572C/G polymorphism and other risk factors of...
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