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Article

Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice.

Journal of cellular physiology - 1 Jul 2009

Sharma Sudarshana M, Sif Said, Ostrowski Michael C, Sankar Uma

Abstract excerpt

The three basic DNA-binding domain mutations of the microphthalmia-associated transcription factor (Mitf), Mitf(mi/mi), Mitf(or/or), and Mitf(wh/wh) affect osteoclast differentiation with variable penetrance while completely impairing melanocyte development. Mitf(or/or) mice exhibit osteopetrosis...

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Source

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Identifiers

PMID: 19288495
DOI: 10.1002/jcp.21755
PMCID: PMC2852098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19288495-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice.PMID 19288495Read ↗

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The novel mouse microphthalmia mutations Mitfmi-enu5 and Mitfmi-bcc2 produce dominant negative Mitf proteins.Semantic proximity Read ↗

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