Article
Women exposed to single-dose nevirapine in successive pregnancies: effectiveness and nonnucleoside reverse transcriptase inhibitor resistance.
AIDS (London, England) - 27 Apr 2009
Martinson Neil A, Morris Lynn, Johnson Jeffrey, Gray Glenda E, Pillay Visva, Ledwaba Johanna, Dhlamini Puleng, Cohen Sarah, Puren Adrian, Steyn Jan, Heneine Walid, McIntyre James A
Abstract excerpt
OBJECTIVE: To assess the impact of prior exposure to single-dose nevirapine (sdNVP) on mother-to-child transmission and genotypic resistance in HIV-infected women. DESIGN: Prospective study of 120 women exposed to the HIVNET 012 sdNVP regimen in two successive pregnancies and 240 antiretroviral (ARV)-naïve, multiparous women who received sdNVP for the first time. RESULTS: One hundred and eight of 120 and 193 of...
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