Article
Hypermethylation of estrogen receptor-α gene in atheromatosis patients and its correlation with homocysteine
14 Mar 2009
Abstract excerpt
OBJECTIVE: To investigate the aberrant DNA methylation in promoter region of estrogen receptor alpha (ERalpha) in atherosclerosis (As) and the possible involvement of homocysteine (Hcy) in its pathogenesis. METHODS: The blood samples were collected from 54 patients with As approved by carotid colorized ultrasound examination and 28 healthy control subjects. The methylation status of CpG islands in ER-alpha gene...
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