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Article

Effect of MTHFR Gene Polymorphism Impact on Atherosclerosis via Genome-Wide Methylation.

Medical science monitor : international medical journal of experimental and clinical research - 1 Feb 2016

Lin Xuefeng, Zhang Wei, Lu Qun, Lei Xinjun, Wang Tingzhong, Han Xuanmao, Ma Aiqun

Abstract excerpt

BACKGROUND: Atherosclerosis seriously threats human health. Homocysteine is an independent risk factor closely related to DNA methylation. MTHFR C667T loci polymorphism is closely associated with homocysteine level. This study aimed to investigate the relationship among MTHFR C667T loci polymorphism, genome-wide methylation, and atherosclerosis. MATERIAL/METHODS: Blood sample was collected from 105 patients with...

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Share to Atherosclerosis
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Loci

Share to Genome, Human

Share to Linkage Disequilibrium

Share to Long Interspersed Nucleotide Elements

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Source

Open in PubMed Open full text

Identifiers

PMID: 26828698
DOI: 10.12659/msm.895296
PMCID: PMC4743680

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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