Article
Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies.
Lipids in health and disease - 23 Jan 2006
Sharma Priyanka, Senthilkumar R D, Brahmachari Vani, Sundaramoorthy Elayanambi, Mahajan Anubha, Sharma Amitabh, Sengupta Shantanu
Abstract excerpt
Homocysteine is an independent risk factor for cardiovascular diseases. It is also known to be associated with a variety of complex disorders. While there are a large number of independent studies implicating homocysteine in isolated pathways, the mechanism of homocysteine induced adverse effects are not clear. Homocysteine-induced modulation of gene expression through alteration of methylation status or by...
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