Article
Novel metabolic activity indicator in Streptococcus mutans biofilms.
Journal of microbiological methods - 1 Apr 2009
Deng D M, Hoogenkamp M A, Ten Cate J M, Crielaard W
Abstract excerpt
Antimicrobial resistance of micro-organisms in biofilms requires novel strategies to evaluate the efficacy of caries preventive agents in actual biofilms. Hence we investigated fluorescence intensity (FI) in Streptococcus mutans biofilms constitutively expressing green fluorescent protein (GFP). Upon addition of glucose FI in these biofilms increased significantly to steady state levels. FI-increase could be...
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