Article
Microbial conversion of glucose to a novel chemical building block, 2-pyrone-4,6-dicarboxylic acid.
Metabolic engineering - 1 Jan 2000
Nakajima Masahiro, Nishino Yukari, Tamura Masatsugu, Mase Kohei, Masai Eiji, Otsuka Yuichiro, Nakamura Masaya, Sato Kanna, Fukuda Masao, Shigehara Kiyotaka, Ohara Seiji, Katayama Yoshihiro, Kajita Shinya
Abstract excerpt
2-Pyrone-4,6-dicarboxylic acid (PDC) is a catabolic intermediate in Sphingobium sp. SYK-6 (previously characterized as Sphingomonas paucimobilis SYK-6), which is a degrader of lignin-derived aromatic compounds. Recently, PDC has been also characterized as a novel starting material for several potentially useful synthetic polymers. In a previous study, we constructed a biosynthetic system in which PDC was...
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