Article
Order propensity of an intrinsically disordered protein, the cyclin-dependent-kinase inhibitor Sic1.
Proteins - 15 Aug 2009
Brocca Stefania, Samalíková Mária, Uversky Vladimir N, Lotti Marina, Vanoni Marco, Alberghina Lilia, Grandori Rita
Abstract excerpt
Intrinsically disordered proteins (IDPs) carry out important biological functions and offer an instructive model system for folding and binding studies. However, their structural characterization in the absence of interactors is hindered by their highly dynamic conformation. The cyclin-dependent-...
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