Article
Pathogenic mutations of nuclear genes associated with mitochondrial disorders.
Acta biochimica et biophysica Sinica - 1 Mar 2009
Zhu Xiaoyu, Peng Xuerui, Guan Min-Xin, Yan Qingfeng
Abstract excerpt
Mitochondrial disorders are clinical phenotypes associated with mitochondrial dysfunction, which can be caused by mutations in mitochondrial DNA (mtDNA) or nuclear genes. In this review, we summarized the pathogenic mutations of nuclear genes associated with mitochondrial disorders. These nuclear genes encode, components of mitochondrial translational machinery and structural subunits and assembly factors of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.