Article
Analysis of the methylation profiles in imprinted genes applicable to parental allele discrimination.
Legal medicine (Tokyo, Japan) - 1 Apr 2009
Nakayashiki Nori, Takamiya Masataka, Shimamoto Kirito, Aoki Yasuhiro
Abstract excerpt
This study investigated the distribution of methylated CpGs around several SNPs in five imprinted genes, which are useful to discriminate the differentially methylated parental allele (DMPA), by bisulfite-sequencing method. The genomic DNAs from peripheral blood, saliva and relatively fresh postmortem tissues except for testis showed a differentially methylated status in each parental allele, however, DNAs from...
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