Article
An overview: from discovery of candidate mutations to disease modeling and transformation mechanisms of acute leukemia.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
So Chi Wai Eric
Abstract excerpt
Acute leukemia is an aggressive form of hematological malignancy, which is characterized and classified into different subtypes according to the morphology and immunophenotype of the leukemic blasts. However in the past decade, it became clear that it is the genetic makeup and probably the origin of leukemic stem cells, which determine the phenotype, aggressiveness, and prognosis of the disease. To further...
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