Lack of association of DRD2 rs1800497 (Taq1A) polymorphism with smoking cessation in a nicotine replacement therapy randomized trial.

doi:10.1093/ntr/ntp007

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Article

Lack of association of DRD2 rs1800497 (Taq1A) polymorphism with smoking cessation in a nicotine replacement therapy randomized trial.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Apr 2009

Munafò Marcus R, Johnstone Elaine C, Murphy Michael F G, Aveyard Paul

Abstract excerpt

INTRODUCTION: We previously reported evidence that the T allele of the dopamine type-2 receptor (DRD2) rs1800497 polymorphism is associated with improved response to nicotine replacement therapy (NRT) relative to placebo and that this association may only be present in females. However, evidence of the poor replication validity of genetic association studies is growing, particularly among those that report...

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Identifiers

PMID: 19273465
DOI: 10.1093/ntr/ntp007

Genes

DRD2

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