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Article

Aggregation of copper-zinc superoxide dismutase in familial and sporadic ALS.

Antioxidants & redox signaling - 1 Jul 2009

Chattopadhyay Madhuri, Valentine Joan Selverstone

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease characterized by the selective death of motor neurons. While the most common form of ALS is sporadic and has no known cause, a small subset of cases is familial because of underlying genetic mutations. The best-studies example of familial ALS is that caused by mutations in the protein copper-zinc superoxide dismutase. The...

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Source

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Identifiers

PMID: 19271992
DOI: 10.1089/ars.2009.2536
PMCID: PMC2842589

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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