Article
Discrimination of aliphatic substrates by a single amino acid substitution in Bacillus badius and Bacillus sphaericus phenylalanine dehydrogenases.
Bioscience, biotechnology, and biochemistry - 23 Mar 2009
Tachibana Shinjiro, Kuwamori Yuko, Asano Yasuhisa
Abstract excerpt
Replacement of glycine by serine at positions 123 and 124 of phenylalanine dehydrogenases from Bacillus badius and Bacillus sphaericus respectively strikingly decreased enzyme activity toward aromatic amino acids and resulted in an elevation of relative activity toward aliphatic amino acids. The...
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