Article
Neurexin IV and Wrapper interactions mediate Drosophila midline glial migration and axonal ensheathment.
Development (Cambridge, England) - 1 Apr 2009
Wheeler Scott R, Banerjee Swati, Blauth Kevin, Rogers Stephen L, Bhat Manzoor A, Crews Stephen T
Abstract excerpt
Glia play crucial roles in ensheathing axons, a process that requires an intricate series of glia-neuron interactions. The membrane-anchored protein Wrapper is present in Drosophila midline glia and is required for ensheathment of commissural axons. By contrast, Neurexin IV is present on the membranes of neurons and commissural axons, and is highly concentrated at their interfaces with midline glia. Analysis of...
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