Article
Emerging fluoroquinolone-non-susceptible group A streptococci in two different paediatric populations.
International journal of antimicrobial agents - 1 Jul 2009
Smeesters Pierre Robert, Vergison Anne, Junior Dioclécio Campos, Van Melderen Laurence
Abstract excerpt
Clonal emergence of group A streptococci (GAS) with reduced susceptibility to fluoroquinolones (FQs) has been increasingly reported. Non-susceptibility is associated with various point mutations in the target-encoding genes and has only been described in a few emm types. We used a well-characterised GAS clinical paediatric collection from Brussels (Belgium) and Brasília (Brazil) to analyse the molecular basis of...
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