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Article

Simultaneous accumulation and degradation of polyhydroxyalkanoates: futile cycle or clever regulation?

Biomacromolecules - 13 Apr 2009

Ren Qun, de Roo Guy, Ruth Katinka, Witholt Bernard, Zinn Manfred, Thöny-Meyer Linda

Abstract excerpt

The regulation of medium-chain-length polyhydroxyalkanoates (mcl-PHA) metabolism in Pseudomonas putida GPo1 was studied by analysis of enzymes bound to PHA granules and enzymes involved in fatty acid oxidation. N-terminal sequencing of granule-bound enzymes revealed the presence of PHA polymerase (PhaC) and PHA depolymerase (PhaZ) and an acyl-CoA synthetase (ACS1), which recently was found to be associated with...

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PMID: 19267463
DOI: 10.1021/bm801431c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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