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Article

Smallpox virus plaque phenotypes: genetic, geographical and case fatality relationships.

The Journal of general virology - 1 Apr 2009

Olson Victoria A, Karem Kevin L, Smith Scott K, Hughes Christine M, Damon Inger K

Abstract excerpt

Smallpox (infection with Orthopoxvirus variola) remains a feared illness more than 25 years after its eradication. Historically, case-fatality rates (CFRs) varied between outbreaks (<1 to approximately 40 %), the reasons for which are incompletely understood. The extracellular enveloped virus (EEV) form of orthopoxvirus progeny is hypothesized to disseminate infection. Investigations with the closely related...

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Identifiers

PMID: 19264626
DOI: 10.1099/vir.0.008169-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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