Article
Sheeppox virus kelch-like gene SPPV-019 affects virus virulence.
Journal of virology - 1 Oct 2007
Balinsky C A, Delhon G, Afonso C L, Risatti G R, Borca M V, French R A, Tulman E R, Geary S J, Rock D L
Abstract excerpt
Sheeppox virus (SPPV), a member of the Capripoxvirus genus of the Poxviridae, is the etiologic agent of a significant disease of sheep in the developing world. Genomic analysis of pathogenic and vaccine capripoxviruses identified genes with potential roles in virulence and host range, including three genes with similarity to kelch-like genes of other poxviruses and eukaryotes. Here, a mutant SPPV with a deletion...
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