Article
Ethnic variation of the HLA-G*0105N allele in two Chinese populations.
Tissue antigens - 1 Mar 2009
Lin A, Li M, Xu D-P, Zhang W-G, Yan W-H
Abstract excerpt
Unlike high polymorphic classical human leukocyte antigen (HLA) class I molecules, the genetic polymorphism of HLA-G is very limited. However, the prevalence of HLA-G alleles among different ethnic populations varied dramatically. The HLA-G null allele (HLA-G*0105N) is defined by a cytosine deletion (Delta C) at position 1597 in exon 3, which disrupts the reading frame and alters the expression of HLA-G proteins....
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