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Article

X chromosome number causes sex differences in gene expression in adult mouse striatum

1 Feb 2009

Abstract excerpt

Previous research suggests that sex differences in the nigrostriatal system are created by direct effects of the sex chromosomes (XX vs. XY), independent of the action of gonadal hormones. Here we tested for sex chromosome effects on expression of three mRNAs in the striatum and nucleus accumbens of adult mice of the four core genotypes model (XX and XY gonadal males, XX and XY gonadal females). Mice were...

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PMID: 19250439
DOI: 10.1111/j.1460-9568.2009.06610.x

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