Article
Sexually dimorphic expression of Usp9x is related to sex chromosome complement in adult mouse brain.
The European journal of neuroscience - 1 Jun 2005
Xu J, Taya S, Kaibuchi K, Arnold A P
Abstract excerpt
We found the expression of Usp9x, an X-linked gene which encodes a ubiquitin protease implicated in synaptic development, to be significantly higher in the adult female mouse brains than in male brains. The sex difference in expression of Usp9x was localized to specific brain regions such as neocortex. Furthermore, in gonadally intact and gonadectomized mice, XX mice expressed Usp9x mRNA and protein more highly...
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