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Article

Impact of X/Y genes and sex hormones on mouse neuroanatomy.

NeuroImage - 1 Jun 2018

Vousden Dulcie A, Corre Christina, Spring Shoshana, Qiu Lily R, Metcalf Ariane, Cox Elizabeth, Lerch Jason P, Palmert Mark R

Abstract excerpt

Biological sex influences brain anatomy across many species. Sex differences in brain anatomy have classically been attributed to differences in sex chromosome complement (XX versus XY) and/or in levels of gonadal sex steroids released from ovaries and testes. Using the four core genotype (4CG) mouse model in which gonadal sex and sex chromosome complement are decoupled, we previously found that sex hormones and...

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PMID: 29501873
DOI: 10.1016/j.neuroimage.2018.02.051

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