Article
Identification of neisserial DNA binding components.
Microbiology (Reading, England) - 1 Mar 2009
Lång Emma, Haugen Kristine, Fleckenstein Burkhard, Homberset Håvard, Frye Stephan A, Ambur Ole Herman, Tønjum Tone
Abstract excerpt
Neisseria meningitidis, a causative agent of meningitis and septicaemia, expresses type IV pili, a feature correlating with the uptake of exogenous DNA from the environment by natural transformation. The outer membrane complex PilQ, through which pili are extruded and retracted, has previously been shown to bind DNA in its pore region. In order to further elucidate how DNA is transported across the membranes, we...
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