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Article

Plectin contributes to mechanical properties of living cells.

American journal of physiology. Cell physiology - 1 Apr 2009

Na Sungsoo, Chowdhury Farhan, Tay Bernard, Ouyang Mingxing, Gregor Martin, Wang Yingxiao, Wiche Gerhard, Wang Ning

Abstract excerpt

Plectin is a 500-kDa cross-linking protein that plays important roles in a number of cell functions including migration and wound healing. We set out to characterize the role of plectin in mechanical properties of living cells. Plectin(-/-) cells were less stiff than plectin(+/+) cells, but the slopes of the two power laws in response to loading frequencies (0.002-1,000 Hz) were similar. Plectin(-/-) cells lost...

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Identifiers

PMID: 19244477
DOI: 10.1152/ajpcell.00604.2008
PMCID: PMC2670656

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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