Article
Nuclear shuttling of She2p couples ASH1 mRNA localization to its translational repression by recruiting Loc1p and Puf6p.
Molecular biology of the cell - 1 Apr 2009
Shen Zhifa, Paquin Nicolas, Forget Amélie, Chartrand Pascal
Abstract excerpt
The transport and localization of mRNAs results in the asymmetric synthesis of specific proteins. In yeast, the nucleocytoplasmic shuttling protein She2 binds the ASH1 mRNA and targets it for localization at the bud tip by recruiting the She3p-Myo4p complex. Although the cytoplasmic role of She2p...
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