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Article

Gene-expression profiling of peripheral blood mononuclear cells in sepsis*

23 Feb 2009

Abstract excerpt

OBJECTIVES: It has been shown that gene-expression profiling of circulating neutrophils could identify signature genes of sepsis. However, whether similar transcriptional changes occurred in peripheral blood mononuclear cells (PBMC) was not known. Using microarray technology, we performed gene-expression profiling of PBMC to identify signature genes that distinguish sepsis from noninfectious causes of systemic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19237892
DOI: 10.1097/ccm.0b013e31819b52fd

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