Article
Behavior and stress reactivity in mouse strains with mitochondrial DNA variations.
Annals of the New York Academy of Sciences - 1 Feb 2009
Gimsa Ulrike, Kanitz Ellen, Otten Winfried, Ibrahim Saleh M
Abstract excerpt
We studied the behavior and neuroendocrine regulation under social disruption stress of C57BL/6J mice in which mitochondria were substituted by mitochondria from AKR/J or FVB/N strains. C57BL/6J-mt(FVB/N) mice were significantly more anxious in the elevated plus-maze test than C57BL/6J-mt(AKR/J) and C57BL/6J mice at base line. In addition, they showed a reduced corticosterone response and an activation of...
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