Article
Cardiac cushions modulate action potential phenotype during heart development [corrected].
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2009
Polo-Parada Luis, Zhang Xiaolin, Modgi Amol
Abstract excerpt
The extracellular matrix plays an important role in cardiac function. Its role in the generation and modulation of electrical activity in the early stages of heart development has not been studied extensively. Our study demonstrates that the extracellular matrix in cardiac cushions can alter the action potential phenotype by direct contact with cardiomyocytes from different regions of the heart. We also...
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