Article
A novel Drosophila antisense scaRNA with a predicted guide function.
Gene - 1 May 2009
Tortoriello Giuseppe, Accardo Maria Carmela, Scialò Filippo, Angrisani Alberto, Turano Mimmo, Furia Maria
Abstract excerpt
A significant portion of eukaryotic small ncRNA transcriptome is composed by small nucleolar RNAs. From archaeal to mammalian cells, these molecules act as guides in the site-specific pseudouridylation or methylation of target RNAs. We used a bioinformatics search program to detect Drosophila putative orthologues of U79, one out of ten snoRNAs produced by GAS5, a human ncRNA involved in apoptosis, susceptibility...
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