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Article

Genetic variants of beta-globin gene in Thai malaria patients.

The Southeast Asian journal of tropical medicine and public health - 1 Jan 2003

Naka Izumi, Ohashi Jun, Patarapotikul Jintana, Hananantachai Hathairad, Looareesuwan Sornchai, Tokunaga Katsushi

Abstract excerpt

Hemoglobin E (E26K variant of beta-globin gene) causing hemoglobinopathy is commonly observed in parts of Thailand, regardless of the hematologic disadvantage of the homozygotes. In order to detect further variants of the beta-globin gene, we performed variation screening for exon 1 of the beta-globin gene in 64 adult patients with P. falciparum malaria, living in northwest Thailand. We identified E26K and two...

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PMID: 19230568

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