Article
Molecular analysis of beta-thalassemia in South Vietnam.
Hemoglobin - 1 Aug 2001
Le T H, Pissard S, Pham H V, Lacombe C, Truong D H, Goossens M, Truong D K
Abstract excerpt
The high prevalence of beta-thalassemia in Southeast Asia is a major public health problem. Development of genetic counseling and prenatal diagnosis programs is a priority. To provide the groundwork for such programs in South Vietnam, we determined the spectrum of beta-thalassemia mutations in 35 severely affected patients and their relatives. We identified six different beta-thalassemia alleles (five beta(0) and...
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