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Article

Bax shuttling after rotenone treatment of neuronal primary cultures: effects on cell death phenotypes.

Journal of neuroscience research - 1 Jul 2009

Gill Martin B, Perez-Polo J Regino

Abstract excerpt

Neonatal (P7) brain hypoxia-ischemia (HI) induces intracellular Bax protein shifts to the nucleus, mitochondria, and endoplasmic reticulum (ER), where it triggers the activation of the respective cell death signaling cascades. When compared with HI-treated rat pups, 100% O(2) resuscitation of HI-treated rat pups increases HI-induced ER Bax levels, ER-mediated cell death signaling, and resultant lesion volume and...

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Identifiers

PMID: 19224578
DOI: 10.1002/jnr.22019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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