Article
Bax shuttling after neonatal hypoxia-ischemia: hyperoxia effects.
Journal of neuroscience research - 1 Dec 2008
Gill Martin B, Bockhorst Kurt, Narayana Ponnada, Perez-Polo J Regino
Abstract excerpt
Perinatal hypoxia-ischemia (HI) occurs in 0.2%-0.4% of all live births, with 100% O(2) resuscitation (HHI) remaining a standard clinical treatment. HI produces a broad spectrum of neuronal death phenotypes ranging from a more noninflammatory apoptotic death to a more inflammatory necrotic cell death that may be responsible for the broad spectrum of reported dysfunctional outcomes. However, the mechanisms that...
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